New downstream synthetic route of Methyl 2-(2-chloroethoxy)acetate

Reference of 83881-47-4, These common heterocyclic compound, 83881-47-4, name is Methyl 2-(2-chloroethoxy)acetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Reference of 83881-47-4, These common heterocyclic compound, 83881-47-4, name is Methyl 2-(2-chloroethoxy)acetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Alkylation of 2-Fluoro-5-nitro-phenylamine with (2-Chloro-ethoxy)-acetic acid methyl ester in an inert solvent in the presence of base will give [2-(2-Fluoro-5-nitro-phenylamino)-ethoxy]-acetic acid methyl ester.

The synthetic route of 83881-47-4 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Drug Innovation & Design, Inc.; US2003/138432; (2003); A1;,
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