Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 909563-22-0, name is Methyl 4-amino-2-isopropoxybenzoate, A new synthetic method of this compound is introduced below., Safety of Methyl 4-amino-2-isopropoxybenzoate
To a solution of methyl 4-amino-2-(propan-2-yloxy)benzoate (CAS Registry Number 909563-22-0) (2.33 g, 11.1 mmol) in ethyl acetate (25 mL), N-chlorosuccinimide (1.5 g, 11 mmol) was added, followed by heating at 50 C. After completion of the reaction, a residue obtained through concentration of the reaction solution under reduced pressure was purified by silica gel column chromatography [elution solvent: n-hexane/ethyl acetate=100/0-0/100 (V/V)] to obtain 2.7 g (quantitative yield) of the title compound in the form of a solid. (0297) MS m/z: 244, 246 (M+H)+.
The synthetic route of 909563-22-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Daiichi Sankyo Company, Limited; Soneda, Tsuyoshi; Sakai, Hiroki; Matsumoto, Koji; Tanaka, Naomi; Fukunaga, Taichi; (39 pag.)US2019/365688; (2019); A1;,
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