Synthetic Route of 3195-24-2, These common heterocyclic compound, 3195-24-2, name is Diethyl 2,2-diallylmalonate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: In a 10 mL tube, the supported catalyst (0.002 mmol Ru) was dried for 1 h under vacuum (1.0 mbar). Then a solution of diene (0.1 mmol) in dry and degassed solvent (1 mL) was transferred via a cannula to the tube containing the catalyst under argon. The resulting suspension was stirred at the target temperature and the conversion was monitored by GC until the end of the experiment. At this time, the stirring was stopped, the material was left to settle and the solution was filtered via a cannula under nitrogen. The recovered catalyst was washed with dry and degassed solvent (3×3 mL), dried under vacuum and directly used in the next cycle. The filtrates were concentrated under reduced pressure to afford the corresponding RCM product, whose yield was determined by 1H NMR spectroscopy.
The synthetic route of 3195-24-2 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Monge-Marcet, Amalia; Pleixats, Roser; Cattoen, Xavier; Wong Chi Man, Michel; Tetrahedron; vol. 69; 1; (2013); p. 341 – 348;,
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