Related Products of 32864-38-3,Some common heterocyclic compound, 32864-38-3, name is tert-Butyl ethyl malonate, molecular formula is C9H16O4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
To a stirred solution of S3 (1.88 g, 10 mmol) in 30 mL of MeCN at 0 °C was added p-ABSA (3.6 g, 15 mmol) andEt3N (4.2 mL, 30 mmmol). After stirring the reaction mixture at 0 °C 1 h, the mixture was warmed up to rt andstirred for 13 h. The mixture was filtered through a pad of Celite and the filtrate was concentrated in vacuo. Thecrude product was purified by silica gel column chromatography (nhexane/AcOEt = 15/1) to give the titlecompound (1.93 g, 90percent) as a pale yellow oil.
The synthetic route of 32864-38-3 has been constantly updated, and we look forward to future research findings.
Reference:
Article; March, Taryn; Murata, Akihiro; Kobayashi, Yusuke; Takemoto, Yoshiji; Synlett; vol. 28; 11; (2017); p. 1295 – 1299;,
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