Related Products of 56441-97-5,Some common heterocyclic compound, 56441-97-5, name is Methyl 4-(benzyloxy)-3-methoxybenzoate, molecular formula is C16H16O4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
4.1.4 Methyl 4-benzyloxy-5-methoxy-2-nitrobenzoate (12) To a suspension of intermediate 11 (10.1 g, 37 mmol) in AcOH (100 mL) was slowly added 70% HNO3 (20 mL). Subsequently, the mixture was heated to 50 C for 5 h, then cooled to room temperature and poured into ice water (500 mL). After stirring for 1 h, the resulting precipitate was filtered off, washed with water and dried to obtain the nitro compound 12 as a white solid. Yield: 86%, mp: 126-128 C.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Methyl 4-(benzyloxy)-3-methoxybenzoate, its application will become more common.
Reference:
Article; Cheng, Weiyan; Yuan, Youting; Qiu, Ni; Peng, Peng; Sheng, Rong; Hu, Yongzhou; Bioorganic and Medicinal Chemistry; vol. 22; 24; (2014); p. 6796 – 6805;,
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