New downstream synthetic route of Ethyl 12-bromododecanoate

According to the analysis of related databases, 72338-48-8, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 72338-48-8, name is Ethyl 12-bromododecanoate, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C14H27BrO2

c) Synthesis of ethyl 13-(diethoxyphosphoryl)tridecanoate In a single-neck flask with a reflux condenser, ethyl 12-bromododecanoate is weighed (1.8 g, 7.37 mmol) and triethyl phosphite (2.6 mL, 15 mmol) is added. The reaction mixture is brought to 150C and left stirring under a static head of nitrogen. After 24 hours the one neck balloon is attached to the high vacuum pump to eliminate volatile products and the resulting dense oil is directly loaded with column chromatography on silica gel. It is eluted with a mixture of ethyl acetate/petroleum ether 1/1 which leads to the isolation of 2.5 g (yield 94%) of ethyl 13-(diethoxyphosphoryl)tridecanoate as a colourless oil.

According to the analysis of related databases, 72338-48-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Colorobbia Italia S.p.a.; EP1979365; (2012); B1;,
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