Synthetic Route of 50893-36-2,Some common heterocyclic compound, 50893-36-2, name is 1-Chloroethyl ethyl carbonate, molecular formula is C5H9ClO3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
EXAMPLE 4 Preparation of ethyl N,N-di-n-butylcarbamate To a solution of 6.5 g (0.05 mole) of di-n-butylamine and 5.56 g (0.055 mole) of triethylamine in 40 ml of THF, 8.4 g (0.055 mole) of alpha-chloroethyl ethyl carbonate dissolved in 10 ml of THF are added dropwise and with stirring while the temperature is maintained at 5¡ã-10¡ã C. The mixture is allowed to return to room temperature, and is maintained with stirring at this temperature for 2 hours. After removal of the precipitate by filtration, evaporation of the solvent and distillation under reduced pressure, 6.3 g (63percent yield) of the expected carbamate are collected. B.p. 76¡ã C./26.6 Pa (0.2 mm Hg).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1-Chloroethyl ethyl carbonate, its application will become more common.
Reference:
Patent; Societe Nationale des Poudres et Explosifs; US4725680; (1988); A;,
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