In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 52727-57-8, name is Methyl 2-amino-5-bromobenzoate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C8H8BrNO2
A N2 degassed solution of methyl 2-amino-5-bromobenzoate (2.8 g) in 10 mL 1 pyridine was cooled to 0C before the drop wise addition of methane sulfonyl chloride (0.9 mL). The reaction mixture was stirred overnight at rt, then diluted with 50 mL ethyl acetate. The organic layer was washed with a saturated solution of Na2C03, with brine, then dried over MgS04 and evaporated to dryness (yield: 82%). LCMS (method B): 305.6 (M-H)” at 1.55 min.
The synthetic route of 52727-57-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; NOVARTIS TIERGESUNDHEIT AG; ELI LILLY AND COMPANY; GAUVRY, Noelle; TAHTAOUI, Chouaib; (57 pag.)WO2016/33341; (2016); A1;,
Ester – Wikipedia,
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