Application of 140-11-4, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 140-11-4, Name is Benzyl acetate, SMILES is CC(OCC1=CC=CC=C1)=O, belongs to esters-buliding-blocks compound. In a article, author is Deng, Qingsong, introduce new discover of the category.
Selective Synthesis of Benzothiophene-Fused Polycyclic, Eight-Membered N-Heterocycles via Amine-Mediated Three-Component Domino Strategy
A product-selective strategy was used to synthesize benzothiophene-fused polycyclic, eight-membered N-heterocycles via a three-component domino reaction of thioisatins under catalyst-free conditions. The reaction between tryptamine, thioisatin, and bromoacetophenone produced benzothiophene-fused polycyclic compounds. In contrast, using D-tryptophan methyl ester hydrochloride instead of tryptamine afforded benzothiophene-fused eight-membered N-heterocycles. DFT calculations showed that the benzothiophene-fused polycyclic compounds formed via the Pictet-Spengler reaction. However, the ester group in D-tryptophan methyl ester hydrochloride changed the reaction pathway and produced benzothiophene-fused eight-membered N-heterocycles.
Application of 140-11-4, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 140-11-4.