Synthetic Route of 141-12-8, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 141-12-8, Name is (Z)-3,7-Dimethylocta-2,6-dien-1-yl acetate, SMILES is CC(OC/C=C(C)CC/C=C(C)/C)=O, belongs to esters-buliding-blocks compound. In a article, author is Api, A. M., introduce new discover of the category.
RIFM fragrance ingredient safety assessment, carbonic acid, 2-hydroxyethyl 5-methyl-2-(1-methylethyl)cyclohexyl ester, CAS registry number 156679-39-9
The existing information supports the use of this material as described in this safety assessment. Carbonic acid, 2-hydroxyethyl 5-methyl-2-(1-methylethypcyclohexyl ester was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from the target and additional material (isomer) menthol ethylene glycol carbonate (CAS # 156324-78-6) show that carbonic acid, 2-hydroxyethyl 5-methyl-2-(1-methylethyl)cyclohexyl ester is not expected to be genotoxic. Data on carbonic acid, 2-hydroxyethyl 5-methyl-2-(1-methylethyl) cyclohexyl ester provide a calculated MOE >100 for the repeated dose toxicity endpoint and show there are no safety concerns for skin sensitization under the current declared levels of use. The reproductive and local respiratory toxicity endpoints were evaluated using TTC for a Cramer Class I material, and the exposure to carbonic acid, 2-hydroxyethyl 5-methyl-2-(1-methylethypcyclohexyl ester is below the TTC (0.03 mg/kg/day and 1.4 mg/day, respectively). The phototoxicity/photoallergenicity endpoints were evaluated based on UV spectra; carbonic acid, 2-hydroxyethyl 5-methyl-2-(1-methylethyl)cyclohexyl ester is not expected to be phototoxic/photoallergenic. The environmental endpoints were evaluated; carbonic acid, 2-hydroxyethyl 5-methyl-2-(1-methylethyl)cydohexyl ester was found not to be PBT as per the IFRA Environmental Standards, and its risk quotients, based on its current volume of use in Europe and North America (i.e., PEC/PNEC), are <1. Synthetic Route of 141-12-8, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 141-12-8 is helpful to your research.