Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 110-42-9, Name is Methyl decanoate, molecular formula is , belongs to esters-buliding-blocks compound. In a document, author is Uyanik, Muhammet, Category: esters-buliding-blocks.
I+/TBHP Catalysis For Tandem Oxidative Cyclization To Indolo[2,3-b]quinolines
We report a chemoselective tandem oxidative cyclization/aromatization of indole derivatives tethered to aniline sulfonamides using catalytic amount of tetrabutylammonium iodide in the presence of tert-butyl hydroperoxide (TBHP) as an oxidant under nearly neutral conditions at room temperature. The corresponding indolo[2,3-b]quinolines were obtained as sulfonate salts, which could be easily isolated in analytically pure form via only a simple filtration of the crude reaction mixture. The natural product quinindoline could be easily obtained after basic work-up of the sulfonate salt. Control experiments revealed that both ionic and radical active species could be generated in situ under mild conditions for the corresponding oxidative transformations to proceed in a chemoselective manner.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 110-42-9, in my other articles. Category: esters-buliding-blocks.