In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 120974-97-2, name is (E)-Methyl 2-(methoxyimino)-2-(o-tolyl)acetate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. category: esters-buliding-blocks
(1) Methyl-(E)-2-(2-tolyl)-2-methoxyiminoacetate (4.74 g) was dissolved in carbon tetrachloride (100 ml), and N-bromosuccinimide (4.89 g) and benzoylperoxide (554 mg) were added thereto. The resultant mixture was heated under reflux for 1 hour and cooled to room temperature. Insoluble materials were removed by filtration. On concentration of the solvent, the residue was purified by silica gel column chromatography with a mixture of hexane and ethyl acetate to give methyl-(E)-2-(2-bromomethylphenyl)-2-methoxyiminoacetate (6.98 g). 1 H-NMR: 3.89 (3H, s), 4.07 (3H, s), 4.34 (2H, s), 7.13-7.17 (1H, m), 7.34-7.47 (3H, m).
The synthetic route of 120974-97-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Shionogi Seiyaku Kabushiki Kaisha; US5185342; (1993); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics