Related Products of 90030-48-1, A common heterocyclic compound, 90030-48-1, name is Sodium 3-methoxy-3-oxopropane-1-sulfinate, molecular formula is C4H7NaO4S, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Intermediate 7 Sodium 1 -methyl-3-sulfinopropanoate (282mg, 1.62mmol) was suspended in DMSO (2.5ml_). To this, (l -bromoethyl)benzene (0.185ml_, 1 .35mmol) was added and the mixture stirred at room temperature for 18 hours. The mixture was poured into water (25ml_) and extracted with diethyl ether. The organic layer was washed with brine, dried with Na2S04, filtered and concentrated in vacuo to give Intermediate 7 (309mg) as an oil. 1 H NMR (CDCIs) delta: 7.50-7.33 (5H, m), 4.23 (1 H, q), 3.68 (3H, s), 3.18-2.94 (2H, m), 2.83-2.56 (2H, m), 1 .80 (3H, d)
The synthetic route of 90030-48-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ANTABIO SAS; LEMONNIER, Marc; DAVIES, David; PALLIN, David; WO2014/198849; (2014); A1;,
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