Synthetic Route of 7686-78-4, The chemical industry reduces the impact on the environment during synthesis 7686-78-4, name is Diethyl 2-vinylcyclopropane-1,1-dicarboxylate, I believe this compound will play a more active role in future production and life.
Preparation method: under an argon atmosphere, add 0.2 mmol of N-pyrimidine porphyrin compound, 0.36 mmol of ethylene cyclopropane compound to a 35 mL Shrek tube.0.008 mmol of [Cp*Rh(CH3CN)3](SbF6)2, 0.08 mmol of 1-adamantanic acid, 0.04 mmol of silver hexafluoroantimonate, methanol 0.5 mL, reacted at 90 C for 12 hours; after the reaction, using acetic acid Ethyl ester was rinsed, concentrated under reduced pressure, and then chromatographed on silica gel (200-300 mesh, eluent: ethyl acetate / petroleum ether gradient elution, ratio: 0/100 to 100/0). The yield was 81% and E/Z > 20:1.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Diethyl 2-vinylcyclopropane-1,1-dicarboxylate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Zhengzhou University; Zhu Xinju; Wang Qiuling; Zhi Changlei; Li Jing; Liu Shuang; Zhao Xuemei; Hao Xinqi; Song Maoping; (15 pag.)CN109180648; (2019); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics