Electric Literature of 14062-18-1, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 14062-18-1 name is Ethyl 2-(4-methoxyphenyl)acetate, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
(3) Dissolve N-(4-methoxy-3,5-dibromophenyl)carbodiimide in 15 times the mass of anhydrous methanol.After adding sodium methoxide NaOMe, stirring at room temperature for 15min, and then adding ethyl 4-methoxyphenylacetate,N-(4-methoxy-3,5-dibromophenyl)carbodiimide,The ratio of sodium methoxide NaOMe and 4-methoxybenzene ethyl acetate material is 1:1:1,Continue the reaction at room temperature for 4h. Evaporate the methanol, add water equal to the volume of methanol, stir for 10min, and filter by suction.Drying to give N-(4-methoxy-3,5-dibromophenyl)2-(4-methoxyphenyl)-2-ethoxycarbonylvinylamine as a white solid;Yield 99%;
At the same time, in my other blogs, there are other synthetic methods of this type of compound, Ethyl 2-(4-methoxyphenyl)acetate, and friends who are interested can also refer to it.
Reference:
Patent; Guangzhou University; Nanjing University; Chen Kun; Xiao Zhuping; Ma Xiang; Fan Jing; Zhu Hailiang; (9 pag.)CN107501174; (2017); A;,
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