Electric Literature of 22223-49-0, The chemical industry reduces the impact on the environment during synthesis 22223-49-0, name is Methyl 2-amino-3-methylbenzoate, I believe this compound will play a more active role in future production and life.
Example 64 – Preparation of methyl 3-methyl-N-(6-methyl-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonyl)anthranilate Methyl 3-methylanthranilate (2.1 g, 13 mmol) was dissolved in 4 ml pyridine and 6-methyl-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonyl chloride was added. After a mild exothermic reaction subsided the reaction mixture was stirred at 50C for 24 hours. The pyridine was removed by evaporation at reduced pressure and the residue was treated with in 10% aqueous sodium bicarbonate. Insouble material was collected by filtration, washed with ether and dried to yield 2.9 (63%) of the desired product as a solid, mp 198.5-205C. An analytical sample was prepared by recrystallization from ethanol to yield a crystalline solid, mp 208.5-210.5C. IR and 1H NMR spectra were in agreement with the assigned structure.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 2-amino-3-methylbenzoate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; THE DOW CHEMICAL COMPANY; EP142152; (1991); B1;,
Ester – Wikipedia,
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