18927-05-4, name is Methyl 3-Methoxyphenylacetate, belongs to esters-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Formula: C10H12O3
[0333] AIBN (10 mg) was added to a solution of (3-Methoxy-phenyl)-acetic acid methyl ester (2g, 11MMOL) in [CCl4] (30ml). The solution was then heated to reflux and NBS (2.3g, 13MMOL) was added in portions. After complete addition the reaction mixture was refluxed for 4h. After cooling, solid residue was filtered off and the filtrate concentrated to yield product BROMO-(3-METHOXY-PHENYL)-ACETIC acid methyl ester, that was washed repeatedly with pet ether.
The synthetic route of 18927-05-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; CHEMOCENTRYX, INC.; WO2003/105853; (2003); A1;,
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