Research on new synthetic routes about 13195-64-7

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Diisopropyl malonate, other downstream synthetic routes, hurry up and to see.

Adding a certain compound to certain chemical reactions, such as: 13195-64-7, name is Diisopropyl malonate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 13195-64-7, HPLC of Formula: C9H16O4

(1) using 830 mmol of sodium hydride as a catalyst,200 mmol of diisopropyl malonate with 440 mmolPropargyl bromide was added to 210 mL of anhydrous acetonitrile in an ice water bath.Stir the reaction for 8 hours.The product was washed with water, extracted with EtOAc EtOAc.Obtaining the product, compound 1;

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Diisopropyl malonate, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Anhui Normal University; Zheng Xiaojie; Hu Yimin; (15 pag.)CN108947828; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics