Introduction of a new synthetic route about 40872-87-5

Statistics shows that Methyl 3-amino-4-chlorobenzoate is playing an increasingly important role. we look forward to future research findings about 40872-87-5.

Reference of 40872-87-5, These common heterocyclic compound, 40872-87-5, name is Methyl 3-amino-4-chlorobenzoate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

EXAMPLE 16: 4-Chloro-3-(cyclohexylaminocarbonylamino)benzoylguanidine hydrochloride was prepared from methyl 4-chloro-3-aminobenzoate and cyclohexyl isocyanate in accordance with variants 3 and 2 B. (Benzoic acid ester intermediate: colorless crystals, m.p. 158 C.) Colorless crystals, m.p. 223 C.

Statistics shows that Methyl 3-amino-4-chlorobenzoate is playing an increasingly important role. we look forward to future research findings about 40872-87-5.

Reference:
Patent; Hoechst Aktiengesellschaft; US5559153; (1996); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics