Application of 6627-89-0, A common heterocyclic compound, 6627-89-0, name is tert-Butyl phenyl carbonate, molecular formula is C11H14O3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
EXAMPLE 2 7-t-Butyloxycarbonylaminoheptanoic Acid 7-Aminoheptanoic acid (20 g., 1.38 * 10-1 moles) was converted to the title compound using the method of Ulf Ragnarrson et al., Org. Syn., 53, 25 (1973), using tetramethylguanidine (17.3 g., 1.49 * 10-1 moles) and t-butylphenylcarbonate (30 g., 1.54 * 10-1 moles) in dimethylsulfoxide (100 ml.) for three days. The product (24 g.) had m.p. 56-58 after recrystallization from ethyl acetate-hexane-ether. Analysis for: C12 H23 NO4. Calculated: C, 58.75; H, 9.45; N, 5.71. Found: C, 59.14; H, 9.61; N, 5.86.
The synthetic route of 6627-89-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; American Home Products Corporation; US4133805; (1979); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics