Adding a certain compound to certain chemical reactions, such as: 617-52-7, name is Dimethyl itaconate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 617-52-7, COA of Formula: C7H10O4
The procedure of Example D1 is repeated using 0.4 g (2.53 mmol) of dimethyl itaconate as starting material and 8.77 mg (0.0133 mmol) of compound B1 as ligand. The conversion is 100%. Removal of the solvent on a rotary evaporator gives a quantitative yield of (2R)-dimethyl succinate having an enantiomeric purity of 99.5% ee.
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Reference:
Patent; Kesselgruber, Martin; Thommen, Marc; Lotz, Mathias; US2009/270622; (2009); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics