Related Products of 15568-85-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 15568-85-1, name is 5-(Methoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione, This compound has unique chemical properties. The synthetic route is as follows.
The 2- [4-(7-chloro-l,6-naphthyridin-4-yloxy)-2-methoxyphenyl] acetic acid used as a starting material was prepared as follows :-; 5-(Methoxymethylidene)-2,2-dimethyl-l,3-dioxane-4,6-dione (11.16 g) was added to a suspension of 2,6~dichloropyridine-4-amine (8.15 g) in isopropanol (125 ml) at ambient temperature. The resultant mixture was stirred and heated to 75C for 45 minutes. The mixture was cooled to 1O0C and diluted with diethyl ether. The precipitate was isolated. There was thus obtained 5-[(2,6-dichloropyridin-4-ylamino)methylidene]-2,2-dimethyl- l,3-dioxane-4,6-dione (15.5 g); 1H NMR Spectrum: (DMSOd6) 1.7 (s, 6H)5 7.9 (s, 2H), 8.75 (S5 IH), 11.25 (s, lH).
The chemical industry reduces the impact on the environment during synthesis 5-(Methoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione. I believe this compound will play a more active role in future production and life.
Reference:
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2007/113565; (2007); A1;,
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