Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 14064-10-9, name is Diethyl 2-chloromalonate, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 14064-10-9
A solution of the product of Example 107a (1.2 g, 4.4 mmol) and triethylamine (0.49 g, 4.8 mmol) in dichloromethane (25 ML) was treated dropwise with ethyl chloromalonate (0.73 g, 4.8 mmol), stirred for 2 hr and partitioned between ethyl acetate and water and the layers were separated.The ethyl acetate layer was washed with brine, dried (Na2SO4), and concentrated.The residue was purified by column chromatography on silica gel eluding with hexane and ethyl acetate (3:1) to provide the title compound (1.1 g, 65percent). MS (DCI) m/z 387 (M+H)+.
According to the analysis of related databases, 14064-10-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Pratt, John K.; Betebenner, David A.; Donner, Pemela L.; Green, Brian E.; Kempf, Dale J.; McDaniel, Keith F.; Maring, Clarence J.; Stoll, Vincent S.; Zhang, Rong; US2004/87577; (2004); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics