Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 35613-44-6, name is Methyl 2-(2-aminophenyl)acetate, A new synthetic method of this compound is introduced below., COA of Formula: C9H11NO2
Methyl 2- (2-aminophenyl) acetate (0.71 g, 4.3 mmol) andSodium carbonate (0.16g, 1.6mmol)Dissolved in tetrahydrofuran (10mL),Reduce the temperature to -78 and stir for 1h.2-bromopropionyl chloride (0.77g, 4.5mmol) andTetrahydrofuran (5mL) was mixed slowly and completely within 0.5 hours.After the addition is complete, move to room temperature and stir for 5h.Methyl 2- (2- (2-bromopropionamide) phenyl) acetate (white solid, 1.16 g) was obtained in a yield of 90%.
The synthetic route of 35613-44-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Zhangzhou Sanitation Profession College; Zheng Lulu; Luo Jinhong; Yang Lina; Chen Tongjun; (7 pag.)CN110272351; (2019); A;,
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