Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 17994-94-4, name is Methyl 7-aminoheptanoate hydrochloride, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: Methyl 7-aminoheptanoate hydrochloride
(b) Carbostyril-6-sulfonyl chloride (corresponding to 54) (138mg, 0.57mmol) and then subsequently Et3N (114mg, 3.24mmol) in CH2Cl2 (0.5ml) were added to a solution of 7-aminoheptanoic acid methyl ester hydrochloride (142mg, 0.73mmol) in CH2Cl2 (2ml) at room temperature. The reaction mixture was stirred for 16h at room temperature. H2O (10ml), AcOEt (10ml), and n-hexane (10ml) were then sequentially added to the mixture. The precipitate was gathered, washed with H2O, and dried to afford a pink solid (127mg, 0.35mmol, y. 61%). 1H NMR (300MHz/DMSO-d6) delta 1.15-1.20 (4H, m, CH2¡Á2), 1.29-1.44 (4H, m, CH2¡Á2), 2.22 (2H, t, J=7.2Hz, CH2), 2.72 (2H, q, J=6.0Hz, NCH2), 3.56 (3H, s, OCH3), 6.61 (1H, d, J=9.6Hz, CH=), 7.43 (1H, d, J=8.7Hz ArH), 7.53 (1H, t, J=5.9Hz, NH), 7.84 (1H, dd, J=8.7, 2.1Hz ArH), 8.07 (1H, d, J=9.6Hz, CH=), 8.13 (1H, d, J=2.1Hz, ArH), 12.01 (1H, br, NH).
According to the analysis of related databases, 17994-94-4, the application of this compound in the production field has become more and more popular.
Reference:
Article; Tashima, Toshihiko; Murata, Hiroaki; Kodama, Hidehiko; Bioorganic and Medicinal Chemistry; vol. 22; 14; (2014); p. 3720 – 3731;,
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