In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 4630-82-4 as follows. Computed Properties of C8H14O2
Example 5; Catalytic hydrogenation of various esters using complex [RuCyT?-BINAP)(S,S-DPEN)]; General procedure for the catalytic hydrogenation of methyl benzoate as substrate: Under argon, a Keim autoclave was charged with [RuCl2(i?-BINAP)(dmf)2] (0.01 mmol, 0.05 mol%) and S5S-DPEN (0.01 mmol, 0.05 mol%) followed by THF (2 ml) and the solution stirred for 5 minutes. Then a solution of the desired ester (20 mmol) in THF (2 ml), followed by more THF (2 x 1 ml), and a solution of tridecane (1 mmol) in THF (2 ml), as internal standard, followed by more THF (2 x 1 ml), were successively added to the autoclave. Finally, solid NaOMe (1 mmol, 5 mol%) was added and the autoclave was pressurised with hydrogen gas at 50 bars and placed in a thermostatted oil bath set at 600C. After the mentioned time, the autoclave was removed from the oil bath, and cooled in a cold-water bath. Then, an aliquot (0.4 ml) was taken, diluted with MTBE (5 ml), washed with aq. sat. NH4Cl (5 ml), and filtered over a plug of celite and analyzed by GC.Table 5 : Hydrogenation of various esters using complex [RuCl^-BINAPX^S-DPEN)]Com/Base: molar ratio in ppm relative to the substrate of complex and base. GC: percent of product analysed by GC in the crude reaction mixture. Reaction conditions: H2 gas (50 bars), 600C, NaOMe as base and THF (2 M).
According to the analysis of related databases, 4630-82-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; FIRMENICH SA; WO2008/65588; (2008); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics