Adding some certain compound to certain chemical reactions, such as: 14062-25-0, name is Ethyl 2-(4-bromophenyl)acetate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 14062-25-0. 14062-25-0
(4-bromophenyl)-acetic acid ethyl ester (0.1 g, 0.41 mmol) was dissolved in 1 mLof THF. t-BuOK (0.092 g,0.82 mmol) was added thereto, and iodomethane (0.051 mL, 0.82 mmol) was added thereto at 0C. The mixture wasstirred at room temperature for 18 hours. After addition of 1N HCl and water, the reaction solution was extracted withEtOAc. The organic layer was separated, dried with MgSO4 and purified by column chromatography to obtain the titlecompound (0.047 g, 42%).1H-NMR (CDCl3) delta 7.42 (2H, d), 7.21 (2H, d), 4.11 (2H, q), 1.54 (6H, s), 1.18 (3H, t).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Ethyl 2-(4-bromophenyl)acetate.
Reference:
Patent; LG Chem, Ltd.; KIM, Young Kwan; PARK, Sang Yun; JOO, Hyun Woo; CHOI, Eun Sil; PAEK, Seung Yup; KANG, Seung Wan; KIM, Byung Gyu; LEE, Chang Seok; KIM, Sung Wook; LEE, Sang Dae; (369 pag.)EP3239143; (2017); A2;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics