18013-97-3, name is Diethyl 2,5-dibromoterephthalate, belongs to esters-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 18013-97-3
In a 100 mL Schlenck tube, tin hydride material a1′ (4.7 g) and brominated material b1′ (2.8 g) were successively added.Pd(PPh3)4 (890 mg), toluene (50 mL),Under nitrogen protection, heated under reflux for 40 hours,After removing the toluene by vacuum evaporation and passing through the silica gel column,Dichloromethane as eluent gave the product c1′ (2.5 g, yield 74%) as a yellow solid.
Statistics shows that 18013-97-3 is playing an increasingly important role. we look forward to future research findings about Diethyl 2,5-dibromoterephthalate.
Reference:
Patent; (31 pag.)CN107652304; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics