868-72-4, A common compound: 868-72-4, name is Dimethyl 2,5-dibromohexanedioate, belongs to esters-buliding-blocks compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below.
Dimethyl 2,5-dibromoadipate (437 g) was added to DMF (4 L).Then, cesium carbonate (1 Kg) was slowly added thereto and heated to 120 C, and stirred for 36 hours.After the reaction is over, cool,Pour the reaction solution into 2L of ice water.Extraction with ethyl acetate (800 ml X3).The extracts were also combined, washed, dried and concentrated to give a crude material.Further recrystallization from n-hexane to obtainDimethyl 1,2-cyclobutanedicarboxylate(94g, yield 42%),
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Dimethyl 2,5-dibromohexanedioate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Zhejiang Kaipu Chemical Co., Ltd.; Tan Xianghui; Luo Linfeng; Sun Yanping; Jia Junjian; Zhou Chen; (6 pag.)CN108658762; (2018); A;,
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