15964-79-1, Adding a certain compound to certain chemical reactions, such as: 15964-79-1, name is Methyl 2-(3,4-dimethoxyphenyl)acetate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 15964-79-1.
General procedure: To a mixture corresponding ester (9a-n, 5.0 mmol) and hydrazine monohydrate (15.0 mmol) in ethanol, catalytic amount of pyridine (0.5 mL) was added and refluxed for 10 h. The reaction was monitored by TLC. After the completion of the reaction, ethanol was evaporated from the mixture, water was added and extracted using ethyl acetate. The organic layer was dried over anhydrous sodium sulfate and evaporated under vacuum to get the crude mass. Finally, the products 10a-n were purified using column chromatography. (Yield 80-85%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 2-(3,4-dimethoxyphenyl)acetate, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Manickam, Manoj; Boggu, Pulla Reddy; Pillaiyar, Thanigaimalai; Sharma, Niti; Jalani, Hitesh B.; Venkateswararao, Eeda; Jung, Sang-Hun; Bioorganic and Medicinal Chemistry Letters; vol. 28; 14; (2018); p. 2369 – 2374;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics