In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2150-38-1, name is Methyl 3,4-dimethoxybenzoate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. 2150-38-1
To a solution of methyl 3,5-trimethoxybenzoate (3) (0.89 g, 4.54 mmol) in absolute ethanol (15 mL), 5.7 mL (117.8 mmol) of hydrazine hydrate 64 % was added. The reaction mixture was kept under reflux for 2 hours, when TLC indi-cated the end of the reaction. Then, the media was poured into ice and the resulting precipitate was filtered out afford-ing the 3,5-trimethoxybenzohydrazide (6) obtained as a white solid in 61% yield. 1H NMR and 13C NMR data were observed to be in agreement with previous reports [31].
The synthetic route of 2150-38-1 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Carneiro, Teiliane R.; do Amaral, Daniel N.; Fokoue, Harold H.; Sant?Anna, Carlos M. R.; Porras, Maria L. G.; Oliveira, Augusto C. A.; Cavalcanti, Bruno C.; Pessoa, Claudia; Barreiro, Eliezer J.; Lima, Lidia M.; Letters in drug design and discovery; vol. 15; 7; (2018); p. 778 – 786;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics