2555-28-4,Some common heterocyclic compound, 2555-28-4, name is 7-Methoxy-4-methylcoumarin, molecular formula is C11H10O3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
(0.95 g, 5 mmol) of 4a, 50 mL of xylene was added to a round bottom flask,Stir and heat, so that it gradually dissolved.Then, selenium dioxide (0.55 g, 5 mmol) was added and the reaction was refluxed for 12 h.Stop heating, hot suction filter, the filtrate cold with yellow solid precipitation, The filtrate was concentrated under reduced pressure to give a yellow solid 4b (0.85 g, yield 84%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2555-28-4, its application will become more common.
Reference:
Patent; Shandong He Bentang Biological Technology Co., Ltd.; Pan Xuan; Zhang Chengrui; Wang Huili; (9 pag.)CN106317029; (2017); A;,
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